Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity connected with bortezomib, a proteasome inhibitor Utilized in the cure of many myeloma. Its synthesis or study is crucial for making sure the purity and security from the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug used in the procedure of prostate cancer by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-ten-1): A critical compound from the synthesis of imatinib, a drug that targets specific different types of most cancers, such as Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats various cancers like breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They're intermediates in the synthesis of gemcitabine, an anti-most cancers drug. Their analyze is crucial for optimizing the creation system and making certain large purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is made use of to treat breast cancer, and these intermediates are associated with its generation.
Fulvestrant Intermediates: Fulvestrant is definitely an estrogen receptor antagonist Utilized in the procedure of breast most cancers. A variety of intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug efficient in dealing with cancers for instance ovarian, breast, and lung most cancers.
three. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the cure of colorectal cancer and modest mobile lung cancer.
3-Amino-1-hydroxyadamantane 2-difluoro-D-erythro-pentofuranose-3 (CAS 702-eighty two-nine): This compound is involved with the synthesis of adamantane derivatives, that have various programs, like antiviral Houses.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for form two diabetes that inhibits the enzyme DPP-four to control blood sugar levels.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved with the synthesis of varied gluconic acid derivatives, which might be Employed in meals, pharmaceutical, and industrial apps.
Canagliflozin Intermediate 2: A precursor inside the synthesis of canagliflozin, a medication applied to deal with sort two Cb 7598 diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).